Merimage imaging platform
Merimage is a cutting-edge imaging platform dedicated to marine biology and health research. The services are offered with framwork of EMBRC-France infrastructure. We provide scientists with advanced microscopy tools, technical expertise, and training to support innovation and discovery at local, national, and international levels.
Mission
- Deliver state-of-the-art optical and electron microscopy services.
- Offer scientific and technical expertise in marine biology imaging.
- Ensure high-quality services and foster methodological innovation.
- Support users through training, workshops, and personalized guidance.
Main activities
- Method Development & Expertise
- Applied research projects in microscopy.
- Implementation of complex imaging protocols and new techniques.
- Training & Support
- Tailored scientific and technical assistance.
- Organize workshops and training days for the scientific community.
- Image Acquisition & Analysis
- Optical microscopy: fluorescence, confocal, super-resolution.
- Electron microscopy: TEM, SEM.
- Quantitative and qualitative data analysis.
Networks and Research Infrastructure
Merimage est membre de réseaux et infrastructures de recherche au niveau régional et national.
Contact(s)
- Sophie LepanseResearch Engineer, Head of Merimage Imaging Platform
Services
You can schedule an appointment with the imaging platform engineer to discuss the feasibility of the experiment and determine the terms and conditions for carrying out the work.
Electron Microscopy
- Ultrastructural analysis (Epon, Spurr).
- Cryosubstitution of cryo-fixed samples.
- Ultra(cryo)microtomy: semi-thin and ultra-thin sections.
- Staining with uranyl acetate and lead.
- Negative staining.
- Immunolocalization with colloidal gold.
- Endocytosis studies with electron-dense tracers.
- In situ hybridization.
Optical Microscopy
- Visualization of fluorescent molecules.
- Z-stack imaging.
- Time-lapse dynamic process analysis.
- Spectral analysis.
- Mosaic imaging.
- Image processing and analysis.
Equipments
Merimage has a wide range of equipment at its disposal.
Electron Microscopy
- JEOL 1400 Transmission Electron Microscope with HD Gatan cameras.
- Cryo sample holder for cryo-electron microscopy.
- Phenon Scanning Electron Microscope.
- Sample preparation tools: Leica ultra-cryo-microtome, Leica AFS2 cryosubstitution system, Baltec SPD030 critical point dryer.
Optical Microscopy
- Leica TCS SP5 AOBS inverted confocal microscope.
- Leica DMI6000B video microscope.
- Zeiss Discovery stereomicroscope.
- Leica TCS SP8 confocal microscope.
- Imaris analysis workstation.
Requests for services or training must be accompanied by the internal regulations signed by the requesting team’s supervisor.
Transmission electron microscopy
Photo of brown algae Ectocarpus obtained by transmission electron microscopy
Scanning electron microscopy
Photo of wild ivy (Glecoma) obtained by scanning electron microscopy
Team
