Our publications
Roscovitine targets, protein kinases and pyridoxal kinase
S. Bach, M. Knockaert, J. Reinhardt, O. Lozach, S. Schmitt, et al.. Roscovitine targets, protein kinases and pyridoxal kinase. Journal of Biological Chemistry, 2005, 280, pp.31208-31219. ⟨hal-00018751⟩
Mechanism of CDK5/p25 binding by CDK inhibitors
M. Mapelli, L. Massimiliano, C. Crovace, Seeliger M. A., Tsai L. H., et al.. Mechanism of CDK5/p25 binding by CDK inhibitors. Journal of Medicinal Chemistry, 2005, 48, pp.671-679. ⟨hal-00018754⟩
Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases
Brana M. F. Cacho M. Garcia M. L. Mayoral E. P. Lopez B. de Pascual-Teresa B. Ramos A. Acero N. Llinares F. Munoz-Mingarro D. Lozach O. Meijer L.. Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases. Journal of Medicinal Chemistry, 2005, 48, pp.6843-54. ⟨hal-00018920⟩
Screening the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2 kinase
H. Yang, S. Zheng, L. Meijer, Li S. M., S. Leclerc, et al.. Screening the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2 kinase. Journal of Zhejiang University. Science, 2005, 6B, pp.656-663. ⟨hal-00018922⟩
Synthesis of acridinyl-thiazolino derivatives and their evaluation for anti-inflammatory, analgesic and kinase inhibition activities
Sondhi S. M., N. Singh, Lahoti A. M., K. Bajaj, A. Kumar, et al.. Synthesis of acridinyl-thiazolino derivatives and their evaluation for anti-inflammatory, analgesic and kinase inhibition activities. Bioorganic and Medicinal Chemistry, 2005, 13, pp.4291. ⟨hal-00018923⟩
Biosynthesis of new indigoid inhibitors of protein kinases using recombinant cytochrome P450 2A6
Wu Z.L., P. Aryal, O. Lozach, L. Meijer, Guengerich F.P.. Biosynthesis of new indigoid inhibitors of protein kinases using recombinant cytochrome P450 2A6. Chem & Biodiv, 2005, 2, pp.51-65. ⟨hal-00018924⟩
Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes
B. Voigt, L. Meijer, O. Lozach, C. Schachtele, F. Totzke, et al.. Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes. Bioorganic and Medicinal Chemistry Letters, 2005, 15, pp.823-825. ⟨hal-00018927⟩
Le cycle cellulaire et sa régulation. In "Cancérologie Fondamentale".
L. Meijer. Le cycle cellulaire et sa régulation. In "Cancérologie Fondamentale".. J Libbey Eurotext, Paris, 2005, 0, pp.19-29. ⟨hal-00018932⟩
Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-β-carbolines
Marie Laronze, Michel Boisbrun, S. Leonce, B. Pfeiffer, P. Renard, et al.. Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-β-carbolines. Bioorganic and Medicinal Chemistry, 2005, 13, pp.2263-2283. ⟨hal-00020821⟩
Response of the Pacific oyster Crassostrea gigas to hypoxia exposure under experimental conditions.
Elise David, Arnaud Tanguy, Karine Pichavant, Dario Moraga. Response of the Pacific oyster Crassostrea gigas to hypoxia exposure under experimental conditions.. FEBS Journal, 2005, 272 (21), pp.5635-52. ⟨10.1111/j.1742-4658.2005.04960.x⟩. ⟨hal-00750438⟩
Organization and expression of the GSK3/Shaggy kinase gene family in the moss Physcomitrella patens suggest early gene multiplication in land plants and an ancestral response to osmotic stress
O. Richard, N. Paquet, E. Haudecoeur, Bénédicte Charrier. Organization and expression of the GSK3/Shaggy kinase gene family in the moss Physcomitrella patens suggest early gene multiplication in land plants and an ancestral response to osmotic stress. Journal of Molecular Evolution, 2005, 61, pp.99-113. ⟨10.1007/s00239-004-0302-6⟩. ⟨hal-00086917⟩
The endo-beta-agarases AgaA and AgaB from the marine bacterium Zobellia galactanivorans: two paralogue enzymes with different molecular organizations and catalytic behaviours.
M. Jam, D. Flament, J. Allouch, P. Potin, Dolorès Thion, et al.. The endo-beta-agarases AgaA and AgaB from the marine bacterium Zobellia galactanivorans: two paralogue enzymes with different molecular organizations and catalytic behaviours.. Biochemical Journal, 2005, 385, pp.703-713. ⟨hal-00092292⟩