Thematics
Cell differentiation and Cell death
- Ion channel and membrane transport
- Kinase and necroptosis
- Cell physiology in health & diseases
People
Publications
Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy
Lhana Tisseur, Cédric Logé, Sandrine Cojean, Khadidiatou Gassama, Lilian Karcher, et al.. Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy. RSC Medicinal Chemistry, In press, ⟨10.1039/d5md00257e⟩. ⟨hal-05173262⟩
Structured Model Conserving Biomass for the Size-spectrum Evolution in Aquatic Ecosystems
Laura Kanzler, Benoît Perthame, Benoît Sarels. Structured Model Conserving Biomass for the Size-spectrum Evolution in Aquatic Ecosystems. Journal of Mathematical Biology, 2024, 88 (3), pp.26. ⟨10.1007/s00285-023-02043-y⟩. ⟨hal-03895919v2⟩
Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound
C. Kieffer, N. Primas, S. Hutter, A. Merckx, L. Reininger, et al.. Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound. Bioorganic and Medicinal Chemistry, 2024, 102, pp.117654. ⟨10.1016/j.bmc.2024.117654⟩. ⟨hal-04503278⟩
Characterization of cationic conductance in Red Blood Cells; insights from pharmacological and pathophysiological studies
Aline Hatem. Characterization of cationic conductance in Red Blood Cells; insights from pharmacological and pathophysiological studies. Cellular Biology. Sorbonne Université, 2024. English. ⟨NNT : 2024SORUS008⟩. ⟨tel-04563223⟩
Modifying positions 2 or 8 of the imidazo[1,2-a]pyrazine lead compound CTN1122 affects its antileishmanial activity, L-CK1.2 kinase inhibition, and safety profile
Lhana Tisseur, Marc-Antoine Bazin, Sandrine Cojean, Fabrice Pagniez, Cédric Logé, et al.. Modifying positions 2 or 8 of the imidazo[1,2-a]pyrazine lead compound CTN1122 affects its antileishmanial activity, L-CK1.2 kinase inhibition, and safety profile. GP2A 2024, Aug 2024, Coimbra, Portugal. ⟨hal-04708945⟩
The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells
Polina Petkova-Kirova, Nicoletta Murciano, Giulia Iacono, Julia Jansen, Greta Simionato, et al.. The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells. International Journal of Molecular Sciences, 2024, 25 (3), pp.1416. ⟨10.3390/ijms25031416⟩. ⟨hal-04746528⟩