Publications
Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis
Guengerich F. P., Sorrells J. L., S. Schmitt, Krauser J. A., P. Aryal, et al.. Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis. Journal of Medicinal Chemistry, 2004, 47, pp.3236-3241. ⟨hal-00018956⟩
Expression and activity of cyclin-dependent kinases and glycogen synthase kinase-3 during NT2 neuronal differentiation
M. Gompel, C. Soulie, I. Ceballos-Picot, L. Meijer. Expression and activity of cyclin-dependent kinases and glycogen synthase kinase-3 during NT2 neuronal differentiation. Neurosignals, 2004, 13, pp.134-143. ⟨hal-00020117⟩
Meridianins, a new family of protein kinase inhibitors isolated from the ascidian Aplidium meridianum
M. Gompel, M. Leost, De Kier Joffe E. B., L. Puricelli, Franco L. H., et al.. Meridianins, a new family of protein kinase inhibitors isolated from the ascidian Aplidium meridianum. Bioorganic and Medicinal Chemistry Letters, 2004, 14, pp.1703-1707. ⟨hal-00020119⟩
Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins
M. Knockaert, M. Blondel, S. Bach, M. Leost, C. Elbi, et al.. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene, 2004, 23, pp.4400-4412. ⟨hal-00020122⟩
Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors
E. Droucheau, A. Primot, V. Thomas, D. Mattei, M. Knockaert, et al.. Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors. BBA - Biochimica et Biophysica Acta, 2004, 1697, pp.181-196. ⟨hal-00020125⟩
CDK1/cyclin B regulation during oocyte maturation in two closely related lugworm species, Arenicola marina and Arenicola defodiens
F. Chausson, Paterson L. A., Betteley K. A., L. Hannah, L. Meijer, et al.. CDK1/cyclin B regulation during oocyte maturation in two closely related lugworm species, Arenicola marina and Arenicola defodiens. Development, growth & differentiation., 2004, 46, pp.71-82. ⟨hal-00020126⟩
Synthesis and target identification of hymenialdisine analogs
Y. Wan, W. Hur, Cho C. Y., Yehan Liu, Adrian F. J., et al.. Synthesis and target identification of hymenialdisine analogs. Chemistry & biology, 2004, 11, pp.247-259. ⟨hal-00020127⟩
1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3 beta
C. Kunick, K. Lauenroth, M. Leost, L. Meijer, T. Lemcke. 1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3 beta. Bioorganic and Medicinal Chemistry Letters, 2004, 11, pp.413-416. ⟨hal-00020128⟩
Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones
C. Kunick, K. Lauenroth, K. Wieking, X. Xie, C. Schultz, et al.. Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones. Journal of Medicinal Chemistry, 2004, 47, pp.22-36. ⟨hal-00020129⟩
Polyprenyl-hydroquinones and -furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A
I. Erdogan-Orhan, B. Sener, De Rosa S., J. Perez-Baz, O. Lozach, et al.. Polyprenyl-hydroquinones and -furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A. Natural Product Letters, 2004, 18, pp.1-9. ⟨hal-00020132⟩
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
N. Sato, L. Meijer, L. Skaltsounis, P. Greengard, Brivanlou A. H.. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nature Medicine, 2004, 10, pp.55-63. ⟨hal-00020135⟩
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases
P. Polychronopoulos, P. Magiatis, A. L. Skaltsounis, V. Myrianthopoulos, E. Mikros, et al.. Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases. Journal of Medicinal Chemistry, 2004, 47, pp.935-946. ⟨hal-00020137⟩