Publications
Characterization of two T. gondii CK1 isoforms
Donald R. G., T. Zhong, Laurent Meijer, P.A. Liberator. Characterization of two T. gondii CK1 isoforms. Molecular and Biochemical Parasitology, 2005, 141, pp.15-27. ⟨hal-00018742⟩
Structure-aided optimization of kinase inhibitors derived from alsterpaullone
C. Kunick, Z. Zeng, R. Gussio, D. Zaharevitz, M. Leost, et al.. Structure-aided optimization of kinase inhibitors derived from alsterpaullone. ChemBioChem, 2005, 6, pp.1-9. ⟨hal-00018743⟩
Epoxide-containing side chains enhance antiproliferative activity of paullones
X. Xie, T. Lemcke, R. Gussio, Zaharevitz D. W., M. Leost, et al.. Epoxide-containing side chains enhance antiproliferative activity of paullones. European Journal of Medicinal Chemistry, 2005, 40, pp.655-661. ⟨hal-00018745⟩
Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin
Lu H., Chang D. J., B. Baratte, L. Meijer, U. Schulze-Gahmen. Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin. Journal of Medicinal Chemistry, 2005, 48, pp.737-743. ⟨hal-00018747⟩
Roscovitine targets, protein kinases and pyridoxal kinase
S. Bach, M. Knockaert, J. Reinhardt, O. Lozach, S. Schmitt, et al.. Roscovitine targets, protein kinases and pyridoxal kinase. Journal of Biological Chemistry, 2005, 280, pp.31208-31219. ⟨hal-00018751⟩
Mechanism of CDK5/p25 binding by CDK inhibitors
M. Mapelli, L. Massimiliano, C. Crovace, Seeliger M. A., Tsai L. H., et al.. Mechanism of CDK5/p25 binding by CDK inhibitors. Journal of Medicinal Chemistry, 2005, 48, pp.671-679. ⟨hal-00018754⟩
Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases
Brana M. F. Cacho M. Garcia M. L. Mayoral E. P. Lopez B. de Pascual-Teresa B. Ramos A. Acero N. Llinares F. Munoz-Mingarro D. Lozach O. Meijer L.. Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases. Journal of Medicinal Chemistry, 2005, 48, pp.6843-54. ⟨hal-00018920⟩
Screening the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2 kinase
H. Yang, S. Zheng, L. Meijer, Li S. M., S. Leclerc, et al.. Screening the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2 kinase. Journal of Zhejiang University. Science, 2005, 6B, pp.656-663. ⟨hal-00018922⟩
Synthesis of acridinyl-thiazolino derivatives and their evaluation for anti-inflammatory, analgesic and kinase inhibition activities
Sondhi S. M., N. Singh, Lahoti A. M., K. Bajaj, A. Kumar, et al.. Synthesis of acridinyl-thiazolino derivatives and their evaluation for anti-inflammatory, analgesic and kinase inhibition activities. Bioorganic and Medicinal Chemistry, 2005, 13, pp.4291. ⟨hal-00018923⟩
Biosynthesis of new indigoid inhibitors of protein kinases using recombinant cytochrome P450 2A6
Wu Z.L., P. Aryal, O. Lozach, L. Meijer, Guengerich F.P.. Biosynthesis of new indigoid inhibitors of protein kinases using recombinant cytochrome P450 2A6. Chem & Biodiv, 2005, 2, pp.51-65. ⟨hal-00018924⟩
Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes
B. Voigt, L. Meijer, O. Lozach, C. Schachtele, F. Totzke, et al.. Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes. Bioorganic and Medicinal Chemistry Letters, 2005, 15, pp.823-825. ⟨hal-00018927⟩
Le cycle cellulaire et sa régulation. In "Cancérologie Fondamentale".
L. Meijer. Le cycle cellulaire et sa régulation. In "Cancérologie Fondamentale".. J Libbey Eurotext, Paris, 2005, 0, pp.19-29. ⟨hal-00018932⟩