Publications
Synthesis of novel 5-substituted indirubins as protein kinases inhibitors
Anne Beauchard, Yoan Ferandin, Stéphane Frère, Olivier Lozach, Mélina Blairvacq, et al.. Synthesis of novel 5-substituted indirubins as protein kinases inhibitors. Bioorganic and Medicinal Chemistry, 2006, 14 (18), pp.6434-43. ⟨10.1016/j.bmc.2006.05.036⟩. ⟨hal-00169371⟩
3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.
Yoan Ferandin, Karima Bettayeb, Marina Kritsanida, Olivier Lozach, Panagiotis Polychronopoulos, et al.. 3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.. Journal of Medicinal Chemistry, 2006, 49 (15), pp.4638-49. ⟨10.1021/jm060314i⟩. ⟨hal-00169375⟩
Modular asymmetric synthesis of aigialomycin D, a kinase-inhibitory scaffold.
Sofia Barluenga, Pierre-Yves Dakas, Yoan Ferandin, Laurent Meijer, Nicolas Winssinger. Modular asymmetric synthesis of aigialomycin D, a kinase-inhibitory scaffold.. Angewandte Chemie International Edition, 2006, 45 (24), pp.3951-4. ⟨10.1002/anie.200600593⟩. ⟨hal-00169376⟩
(R)-roscovitine (CYC202, Seliciclib) sensitizes SH-SY5Y neuroblastoma cells to nutlin-3-induced apoptosis.
Judit Ribas, Jacint Boix, Laurent Meijer. (R)-roscovitine (CYC202, Seliciclib) sensitizes SH-SY5Y neuroblastoma cells to nutlin-3-induced apoptosis.. Experimental Cell Research, 2006, 312 (12), pp.2394-400. ⟨10.1016/j.yexcr.2006.04.021⟩. ⟨hal-00169378⟩
Analysis of cyclin B1 and CDK activity during apoptosis induced by camptothecin treatment.
A. Borgne, I. Versteege, M. Mahé, A. Studeny, S. Léonce, et al.. Analysis of cyclin B1 and CDK activity during apoptosis induced by camptothecin treatment.. Oncogene, 2006, 25 (56), pp.7361-72. ⟨10.1038/sj.onc.1209718⟩. ⟨hal-00169380⟩
7-Bromoindirubin-3'-oxime induces caspase-independent cell death.
J. Ribas, K. Bettayeb, Y. Ferandin, M. Knockaert, X. Garrofé-Ochoa, et al.. 7-Bromoindirubin-3'-oxime induces caspase-independent cell death.. Oncogene, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩. ⟨hal-00169383⟩
Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp.
Dominique Laurent, Valérie Jullian, Arnaud Parenty, Martine Knibiehler, Dominique Dorin, et al.. Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp.. Bioorganic and Medicinal Chemistry, 2006, 14 (13), pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩. ⟨hal-00169387⟩
Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases.
Sham M Sondhi, Nirupma Singh, Ashok Kumar, Olivier Lozach, Laurent Meijer. Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases.. Bioorganic and Medicinal Chemistry, 2006, 14 (11), pp.3758-65. ⟨10.1016/j.bmc.2006.01.054⟩. ⟨hal-00169388⟩
Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.
Ashraf H Abadi, Sahar M Abou-Seri, Doaa E Abdel-Rahman, Christian Klein, Olivier Lozach, et al.. Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.. European Journal of Medicinal Chemistry, 2006, 41 (3), pp.296-305. ⟨10.1016/j.ejmech.2005.12.004⟩. ⟨hal-00169389⟩
Utilisation de la S-roscovitine pour la fabrication d'un medicament.
Meijer L, S. Timsit, B. Meen. Utilisation de la S-roscovitine pour la fabrication d'un medicament.. Patent n° : FR 06/02773. 2006. ⟨hal-00169578⟩
Indirubin, the red shade of indigo
L. Meijer, N. Guyard, Skaltousnis L.A, G. Eisenbrand. Indirubin, the red shade of indigo. Life in Progress Edition, pp.297, 2006. ⟨hal-00169587⟩
Indirubins as activators of the aryl hydrocarbon receptor signal transduction pathway.
Denison M.S, Han D.H., Nagy S.R., B. Zhao, Baston D.S, et al.. Indirubins as activators of the aryl hydrocarbon receptor signal transduction pathway.. Indirubin, the red shade of indigo, Life in Progress, pp.157-167, 2006. ⟨hal-00169614⟩