Our publications
Analysis of cyclin B1 and CDK activity during apoptosis induced by camptothecin treatment.
A. Borgne, I. Versteege, M. Mahé, A. Studeny, S. Léonce, et al.. Analysis of cyclin B1 and CDK activity during apoptosis induced by camptothecin treatment.. Oncogene, 2006, 25 (56), pp.7361-72. ⟨10.1038/sj.onc.1209718⟩. ⟨hal-00169380⟩
7-Bromoindirubin-3'-oxime induces caspase-independent cell death.
J. Ribas, K. Bettayeb, Y. Ferandin, M. Knockaert, X. Garrofé-Ochoa, et al.. 7-Bromoindirubin-3'-oxime induces caspase-independent cell death.. Oncogene, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩. ⟨hal-00169383⟩
Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp.
Dominique Laurent, Valérie Jullian, Arnaud Parenty, Martine Knibiehler, Dominique Dorin, et al.. Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp.. Bioorganic and Medicinal Chemistry, 2006, 14 (13), pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩. ⟨hal-00169387⟩
Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases.
Sham M Sondhi, Nirupma Singh, Ashok Kumar, Olivier Lozach, Laurent Meijer. Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases.. Bioorganic and Medicinal Chemistry, 2006, 14 (11), pp.3758-65. ⟨10.1016/j.bmc.2006.01.054⟩. ⟨hal-00169388⟩
Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.
Ashraf H Abadi, Sahar M Abou-Seri, Doaa E Abdel-Rahman, Christian Klein, Olivier Lozach, et al.. Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.. European Journal of Medicinal Chemistry, 2006, 41 (3), pp.296-305. ⟨10.1016/j.ejmech.2005.12.004⟩. ⟨hal-00169389⟩
Utilisation de la S-roscovitine pour la fabrication d'un medicament.
Meijer L, S. Timsit, B. Meen. Utilisation de la S-roscovitine pour la fabrication d'un medicament.. Patent n° : FR 06/02773. 2006. ⟨hal-00169578⟩
Indirubin, the red shade of indigo
L. Meijer, N. Guyard, Skaltousnis L.A, G. Eisenbrand. Indirubin, the red shade of indigo. Life in Progress Edition, pp.297, 2006. ⟨hal-00169587⟩
Indirubins as activators of the aryl hydrocarbon receptor signal transduction pathway.
Denison M.S, Han D.H., Nagy S.R., B. Zhao, Baston D.S, et al.. Indirubins as activators of the aryl hydrocarbon receptor signal transduction pathway.. Indirubin, the red shade of indigo, Life in Progress, pp.157-167, 2006. ⟨hal-00169614⟩
Diversity of intracellular mechanisms underlying the anti-tumor properties of indirubins
L. Meijer, J. Shearer, K. Bettayeb, Y. Ferandin. Diversity of intracellular mechanisms underlying the anti-tumor properties of indirubins. Indirubin, the red shade of indigo, Life in Progress, pp.235-246, 2006. ⟨hal-00169625⟩
Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.
Sylvain Routier, Jean-Yves Mérour, Nathalie Dias, Amélie Lansiaux, Christian Bailly, et al.. Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.. Journal of Medicinal Chemistry, 2006, 49 (2), pp.789-99. ⟨10.1021/jm050945x⟩. ⟨hal-00169630⟩
Crystal structure of inactivated Thermotoga maritima invertase in complex with the trisaccharide substrate raffinose
Francois Alberto, Emmanuelle Jordi, Bernard Henrissat, Mirjam Czjzek. Crystal structure of inactivated Thermotoga maritima invertase in complex with the trisaccharide substrate raffinose. Biochemical Journal, 2006, 395 (3), pp.457 - 462. ⟨10.1042/BJ20051936⟩. ⟨hal-01818944⟩
A yeast-based assay to isolate drugs active against mammalian prions
Stéphane Bach, Déborah Tribouillard, Nicolas Talarek, Nathalie Desban, Marc Blondel. A yeast-based assay to isolate drugs active against mammalian prions. Methods, 2006, 39 (1), pp.72-77. ⟨10.1016/j.ymeth.2006.04.005⟩. ⟨hal-02134947⟩