Directeur.trice de recherche CNRS

I am a research scientist at the CNRS since 2002 and leader of the DIPO team. My projects focused on diversity and ecological role of marine parasites.

Main scientific interests

• Diversity/taxonomy of marine parasites
• Intra- and inter- genetic variability and dynamics of blooming microalgae and their parasites.
• Evolutionary processes


• PR2 ( The Protist Ribosomal Reference Database provides an access to unicellular eukaryotes Small SubUnit rRNA and rDNA sequences with curated taxonomy. This database is helpful for environmental metabarcoding approaches.

• Aquasymbio ( Aquasymbio lists known symbioses in aquatic systems. This database is still under construction.


Major current research projects

  • The ANR Hapar project (2014-2019): The paradox of being a specialist for a parasite of marine blooming dinoflagellates. Resources: two genomes/transcriptomes of the parasite Amoebophrya.
  • Paleogenetic approach on ancient DNA (aDNA) to understand past environmental phytoplanktonic communities. Thesis project of Khadidja Klouch (2013-2016), in codirection with Siano Raffaele (Ifremer).



Host-parasite dynamics at different scales

  • François Blanquart, Myriam Valero, Catharina Alves-de-Souza, Aliou Dia, Frédéric Lepelletier, Estelle Bigeard, Christian Jeanthon, Christophe Destombe, Laure Guillou (2016). Evidence for parasite-mediated selection during short-lasting toxic algal blooms. Proceedings of the Royal Society B. 283:20161870.
  • Alves-de-Souza Catharina, David Pecqueur, Emilie Le Floc’h, Sébastien Mas, Cécile Roques, Behzad Mostajir, Francesca Vidussi, Lourdes Velo-Suares, Marc Sourisseau, Eric Fouilland, and Laure Guillou (2015). Parasitic control of red tide dinoflagellates under temporary eutrophication is affected by plankton community structure. PLoS One. 2015; 10(6): e0127623.
  • Yameng Lu, Sylke Wohlrab, Gernot Glöckner, Laure Guillou, Uwe John (2014). Genomic insights in processes driving the infection of Alexandrium tamarense by the parasite Amoebophrya sp. Eukaryotic Cell. 13(11):1439-49. IF=3.586
  • Dia Aliou, Guillou Laure, Mauger Stéphane, Bigeard Estelle, Marie Dominique, Valéro Myriam, Destombe Christophe (2014). Spatiotemporal changes in the genetic diversity of harmful algal blooms caused by the toxic dinoflagellate Alexandrium minutum. Molecular Ecology. 23:549-560. IF=6.275
  • Chambouvet A., Alves-de-Souza C., Cueff V., Marie D., Karpov S., Guillou L. (2011). Interplay between the parasite Amoebophrya sp. (Alveolata) and the cyst formation of the red tide dinoflagellate Scrippsiella trochoidea. Protist. 162:637-649. IF = 4.14
  • Chambouvet A., Morin P., Marie D., Guillou L. (2008). Control of toxic marine dinoflagellate blooms by serial parasitic killers. Science. 322: 1254-1257. IF= 31,20

Taxonomy/diversity of marine parasites and their hosts

  • Le Gac Mickael, Chomérat Nicolas, Malestroit Pascale, Quéré Julien, Siano raffaele, Destombe Christophe, Laure Guillou, Chapelle Annie (2016). Evolutionary processes and cellular functions underlying divergence in Alexandrium minutum. Molecular Ecology. DOI:10.1111/mec.13815
  • Lepelletier Frédéric, Sergey A. Karpov, Sophie Le Panse, Estelle Bigeard, Alf Skovgaard, Christian Jeanthon, Laure Guillou (2014). Parvilucifera rostrata sp. nov. (Perkinsozoa), a novel parasitoid that infects planktonic dinoflagellates. Protist. 165:31-49 IF = 4.14
  • Skovgaard A., Karpov S.A., Guillou L. (2012). The parasitic dinoflagellates Blastodinium spp. inhabiting the gut of marine, planktonic copepods: A review. Frontiers in Microbiology. 28 August 2012, doi: 10.3389/fmicb.2012.00305.
  • Lepelletier Frédéric, Sergey A. Karpov, Elisabeth Alacid, Sophie Le Panse, Estelle Bigeard, Esther Garcés, Christian Jeanthon, Laure Guillou (2014). Dinomyces arenysensis gen. et sp. nov. (Rhizophydiales, Dinomycetaceae fam. nov.), a chytrid infecting marine dinoflagellates. Protist. 165:230-244. IF = 4.14


  • Guillou Laure, Bachar Dipankar, Audic Stéphane, Bass David, Berney Cédric, Bittner Lucie, Boutte Christophe, Burgaud Gaetan, de Vargas Colomban, Decelle Johan, del Campo Javier, Dolan John R., Dunthorn Micah, Edvardsen Bente, Holzmann Maria, Kooistra Wiebe H.C.F., Lara Enrique, Le Bescot Noan, Logares Ramiro, Mahé Frédéric, Massana Ramon, Montresor Marina, Morard Raphael, Not Fabrice, Pawlowski Jan, Probert Ian, Sauvadet Anne-Laure, Siano Raffaele, Stoeck Thorsten, Vaulot Daniel, Zimmermann Pascal and Christen Richard (2013). The protist Ribosomal reference database (PR2): a catalog of unicellular eukaryote small subunit rRNA sequences with curated taxonomy. Nucleic Acids Research, database issue, 41:D597-D604. IF: 8.026.
  • Decelle Johan, Sarah Romac, Rowena F. Stern, Mahdi el Bendif, Adriana Zingone, Stéphane Audic, Michael D Guiry, Laure Guillou, Désiré Tessier, Florence Le Gall, Priscillia Gourvil, Adriana Lopes dos Santos, Ian Probert, Daniel Vaulot, Colomban de Vargas Richard Christen (2015). PhytoREF: a reference database of the plastidial 16S rRNA gene of photosynthetic eukaryotes with curated taxonomy. Molecular Ecology Resources. doi: 10.1111/1755-0998.12401, IF=5.626.