Créé(e) 28/11/2017 Mis à jour 22/08/2023


Marlétaz F, Couloux A, Poulain J, Labadie K, Da Silva C, Mangenot S, Noel B, Poustka AJ, Dru P, Pegueroles C, Borra M, Lowe EK, Lhomond G, Besnardeau L, Le Gras S, Ye T, Gavriouchkina D, Russo R, Costa C, Zito F, Anello L, Nicosia A, Ragusa MA, Pascual M, Molina MD, Chessel A, Di Carlo M, Turon X, Copley RR, Exposito JY, Martinez P, Cavalieri V, Ben Tabou de Leon S, Croce J, Oliveri P, Matranga V, Di Bernardo M, Morales J, Cormier P, Geneviève AM, Aury JM, Barbe V, Wincker P, Arnone MI, Gache C, Lepage T. (2023) Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes. Cell Genom. 3(4):100295. doi: 10.1016/j.xgen.2023.100295.

Cormier P., Boutet A., Colas P., Ruchaud S., Bach S., Thomas W., Egée S., Morales J., Roch F. (2023) The Roscoff Biological Station in the era of cellular and molecular biology: Focus on the 50 last years of research on marine animals. Cah. Biol. Mar. 64: 35-52
DOI: 10.21411/CBM.A.C705BF49

Ribeiro E Silva A, Diallo MA, Sausset A, Robert T, Bach S, Bussière FI, Laurent F, Lacroix-Lamandé S, Silvestre A. (2023) Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts Microbiol Spectr. e0013723. doi: 10.1128/spectrum.00137-23.

Hasanvand Z, Oghabi Bakhshaiesh T, Peytam F, Firoozpour L, Hosseinzadeh E, Motahari R, Moghimi S, Nazeri E, Toolabi M, Momeni F, Bijanzadeh H, Khalaj A, Baratte B, Josselin B, Robert T, Bach S, Esmaeili R, Foroumadi A. (2023) Imidazo[1,2-a]quinazolines as novel, potent EGFR-TK inhibitors: Design, synthesis, bioactivity evaluation, and in silico studies Bioorg Chem. 133:106383. doi: 10.1016/j.bioorg.2023.106383. Epub 2023 Jan 20. PMID: 36764231


Avula S, Peng X, Lang X, Tortorella M, Josselin B, Bach S, Bourg S, Bonnet P, Buron F, Ruchaud S, Routier S, Neagoie C (2022) Design and biological evaluation of substituted 5,7-dihydro-6H-indolo[2,3-c]quinolin-6- one as novel selective Haspin inhibitors. J Enzyme Inhib Med Chem. Vol. 37(1):1632-1650. doi:10.1080/14756366.2022.2082419.

Zeinyeh W, Esvan YJ, Josselin B, Defois M, Baratte B, Knapp S, Chaikuad A, Anizon F, Giraud F, Ruchaud S, Moreau P (2022) Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity. Eur J Med Chem. Vol. 236:114369. doi: 10.1016/j.ejmech.2022.114369.

Pontheaux F, Boulben S, Chassé H, Boutet A, Roch F, Morales J, Cormier P (2022) eIF4B mRNA translation contributes to the cleavage dynamics in early sea urchin embryos. Biology, Vol.11, Issue 10, 1408. doi: 10.3390/biology11101408

Flom H, Adamska M, Lami R, Gazave E, D'Aniello S, Schierwater B, Boutet A (2022) Digital Marine: An online platform for blended learning in a marine experimental biology module, the Schmid Training Course. Bioessays vol 44(5):e2100264. doi: 10.1002/bies.202100264.

Dabbugoddu Brahmaiah, Anagani Kanaka Durga Bhavani, Pasula Aparna, Nangunoori Sampath Kumar, Hélène Solhi d, Rémy Le Guevel, Blandine Baratte, Thomas Robert, Sandrine Ruchaud, Stéphane Bach, Surender Singh Jadav, Chada Raji Reddy, Paul Mosset, Nicolas Gouault, Nicolas Levoin, and René Grée. Structure-Activity Relationship studies around DB18, a potent inhibitor of CLK kinases. Molecules. 2022, 27, 6149. Doi :10.3390/molecules27196149

Mathilde Defois, Chloé Rémondin, Béatrice Josselin, Lionel Nauton, Vincent Théry, Fabrice Anizon, Sandrine Ruchaud, Francis Giraud, Pascale Moreau. Synthesis and kinase inhibitory potencies of pyrazolo[3,4-g]isoquinolines. Molecules. 2022, 27,5578 doi:10.3390/molecules27175578


Pontheaux F, Roch F, Morales J, Cormier P (2021) Echinoderms: Focus on the sea urchin model in cellular and developmental biology. In: Boutet, A. and Schierwater B., eds. Handbook of Established and Emerging Marine Model Organisms in Experimental Biology, CRC Press.

Lund-Ricard Y, Boutet A (2021). Current Trends in Chondrichthyes Experimental Biology. In: Boutet, A. and Schierwater B., eds. Handbook of Established and Emerging Marine Model Organisms in Experimental Biology, CRC Press.

Robert T, Dock-Bregeon AC, Colas P (2021). Functional characterization of CDK10 and Cyclin M truncated variants causing severe developmental disorders. Molecular Genetics & Genomic Medicine, 00, e1782.

Dock-Bregeon AC, Lewis KA, Conte MR (2021) The La-related proteins: structures and interactions of a versatile superfamily of RNA-binding proteins. RNA Biol. 18(2):178-193. doi: 10.1080/15476286.2019.1695712

Juillet C, Ermolenko L, Boyarskaya D, Baratte B, Josselin B, Nedev H, Bach S, Iorga BI, Bignon J, Ruchaud S, Al-Mourabit A (2021) From Synthetic Simplified Marine Metabolite Analogues to New Selective Allosteric Inhibitor of Aurora B Kinase. J Med Chem. doi: 10.1021/acs.jmedchem.0c02064.

Brahmaiah D, Kanaka Durga Bhavani A, Aparna P, Sampath Kumar N, Solhi H, Le Guevel R, Baratte B, Ruchaud S, Bach S, Singh Jadav S, Raji Reddy C, Roisnel T, Mosset P, Levoin N, Grée R. (2021) Discovery of a new anilino-2-quinazoline, as a potent and selective inhibitor of CLK kinases. Bioorganic & Medicinal Chemistry. 202, Vol 31; doi: 10.1016/j.bmc.2020.115962.

Princival I., Princival J., da Silva E., Lima S., Carregos J., de Lucenaa A., Halwass F., Franc J., Ferreir L., Hernandes M., Saraiv K., Peixoto K., Baratte B., Robert T., Bach S., Gomes D., Paiva D., Marchand P., Rodrigues M. and da Silva T. (2021). Streptomyces hygroscopicus UFPEDA 3370: a valuable source of the potent cytotoxic agent nigericin and its evaluation against human colorectal cancer cells. Chem Biol Interact, 333:109316. doi: 10.1016/j.cbi.2020.109316.

Bazin A., Cojean S., Pagniez F., Bernadat G., Cavé C., Ourliac-Garnier I., Nourrisson M.-R., Morgado C., Picot C., Leclercq O., Baratte B., Robert T., Späth G.F., Rachidi N., Bach S., Loiseau P.M., Le Pape P. and Marchand P. (2021). In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition. European Journal of Medicinal Chemistry 210; 112956. Doi: 10.1016/j.ejmech.2020.112956


Lund-Ricard Y., Cormier P., Morales J. and Boutet A. (2020) mTOR signaling at the crossroad between metazoan megeneration and human diseases. Int. J. Mol. Sci. 2020, 21, 2718; doi:10.3390/ijms21082718

Colas P (2020) Cyclin-dependent kinases and rare developmental disorders. Orphanet J Rare Dis. 15(1):203. doi: 10.1186/s13023-020-01472-y.

Brillet K, Martinez-Zapien D, Bec G, Ennifar E, Dock-Bregeon AC, and Lebars I (2020) Different views of the dynamic landscape covered by the 5’-hairpin of the 7SK small nuclear RNA. RNA 26(9):1184-1197. doi:10.1261/rna.074955.120

Feizbakhsh O., Pontheaux F., Glippa V., Morales J., Ruchaud S. , Cormier P. and Roch F. (2020) A peak of H3T3 phosphorylation occurs in synchrony with mitosis in sea urchin early embryos. Cells 9, 898; doi:10.3390/cells9040898

Robert T., Johnson J.L., Guichaoua R., Yaron T.M., Bach S., Cantley L.C. and Colas P. (2020) Development of a CDK10/CycM in vitro kinase screening assay and identification of first small-molecule inhibitors. Front. Chem. 8:147. DOI: 10.3389/fchem.2020.00147

Lizarrondo, J., Dock-Bregeon, A.C., Martino, L. and Conte, M.R. (2020) Structural dynamics in the La-module of the La-related proteins, RNA biology, DOI:10.1080/15476286.2020.1733799

Hasler D., Rajyalakshmi M., Bak M., Lehmann G., Heizinger L, Wang X., Li Z.T., Sement F.M., Bruckmann A., Dock-Bregeon A.C., Merkl R., Kalb R, Grauer E., Kunstmann E., Zavolan M. Mo-Fang Liu, Fischer U., and Meister G. (2020). The Alazami Syndrome-associated protein LARP7 guides U6 small nuclear RNA modification and contributes to splicing robustness. Molecular Cell 77, 1014–1031. DOI:10.1016/j.molcel.2020.01.001

Mokhtari Brikci-Nigassa N, Nauton L, Moreau P, Mongin O, Duval RE, Picot L, Thiéry V, Souab M, Baratte B, Ruchaud S, Bach S, Le Guevel R, Bentabed-Ababsa G, Erb W, Roisnel T, Dorcet V, Mongin F (2020) Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest. Bioorg Chem. 94:103347. doi: 10.1016/j.bioorg.2019.103347.

Qhobosheane MA, Legoabe LJ, Josselin B, Bach S, Ruchaud S, Petzer JP, Beteck RM. (2020) Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors. Bioorg Med Chem.  doi: 10.1016/j.bmc.2020.115468.

Ibrahim N, Bonnet P, Brion JD, Peyrat JF, Bignon J, Levaique H, Josselin B, Robert T, Colas P, Bach S, Messaoudi S, Alami M, Hamze A (2020). Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency. Eur J Med Chem. 199:112355. doi: 10.1016/j.ejmech.2020.112355.

Qhobosheane MA, Legoabe LJ, Josselin B, Bach S, Ruchaud S, Beteck RM (2020) Synthesis and evaluation of C3 substituted chalcone-based derivatives of 7-azaindole as protein kinase inhibitors. Chem Biol Drug Des. doi:10.1111/cbdd.13748.

Benchekroun M, Ermolenko L, Tran MQ, Vagneux A, Nedev H, Delehouzé C, Souab M, Baratte B, Josselin B, Iorga BI, Ruchaud S, Bach S, Al-Mourabit A (2020) Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1. Eur J Med Chem. 201:112337. doi: 10.1016/j.ejmech.2020.112337.

Elie J, Feizbakhsh O, Desban N, Josselin B, Baratte B, Bescond A, Duez J, Fant X, Bach S, Marie D, Place M, Ben Salah S, Chartier A, Berteina-Raboin S, Chaikuad A, Knapp S, Carles F, Bonnet P, Buron F, Routier S, Ruchaud S (2020) Design of new disubstituted imidazo[1,2-b] pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation. J Enzyme Inhib Med Chem. 35(1):1840-1853.  Doi: 10.1080/14756366.2020.1825408

Wilde M., Arzur D., Baratte B., Lefebvre D., Robert T., Roisnel T., Le Jossic-Corcos C., Bach S., Corcos L., Erb W. (2020) Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation. New J. Chem., 44, 19723-19733 doi: 10.1039/D0NJ05334A

Tuescher JM, Tailfeathers D, Kernéis SM, Baratte B, Ruchaud R, Bach B, Pouny I, Sautel F, Golsteyn RM. (2020) The Canadian prairie plant Thermopsis rhombifolia contains luteolin, a flavone that inhibits Cyclin dependent kinase 9 and arrest cells in the G1-phase of the cell cycle. The Journal of Natural Health Product Research. (2) 2:1-14. Doi: 10.33211/jnhpr.12.

Esvan YJ, Josselin B, Baratte B, Bach S, Ruchaud R, Anizon F, Giraud F, Moreau P. Synthesis and kinase inhibitory potencies of new pyrido[3,4-g]quinazolines substituted at the 8-position. Arkivoc. 2020, part vii, 105-116.

Bouattour A, Fakhfakh M, Abid S, Paquin L, Le Guével R, Charlier T, Ruchaud R, Bach B, Bazureau JP, Ammar H. (2020) Synthesis of new 2-phenylamino-4H-chromene-3-carbonitrile derivatives and their effects on tumor cell lines and against protein kinases. International Journal of Organic Chemistry 10, 88-103.

Lassagne F, Duguépéroux C, Roca C, Perez C, Martinez A, Baratte B, Robert T, Ruchaud S, Bach B, Erb W, Roisnel T, Mongin F (2020) From simple quinoxalines to potent oxazolo[5,4-f ] quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3). Org. Biomol. Chem., 18, 154.

Pieterse L., Legoabe L., Beteck R., Josselin B., Bach S. and Ruchaud S. (2020) Synthesis and biological evaluation of 7-azaindole as CDK9/Cyclin T and Haspin inhibitors. Medicinal chemistry research (29), 1449-1462. Doi: 10.1007/s00044-020-02560-1.

Bach S., Colas P., Blondel M. (2020) La levure modèle et outil… aussi pour la recherche thérapeutique. Med Sci (Paris) Volume 36, p504-514. doi:10.1051/medsci/2020077


Röder K, Stirnemann G, Dock-Bregeon AC, Wales DJ, Pasquali S. (2019) Structural transitions in the RNA 7SK 5' hairpin and their effect on HEXIM binding. Nucleic Acids Res. doi: 10.1093/nar/gkz1071.

Dock-Bregeon AC, Lewis KA, Conte MR. (2019) The La-related proteins: structures and interactions of a versatile superfamily of RNA-binding proteins. RNA Biology, doi: 10.1080/15476286.2019.1695712.

Papini D, Fant X, Ogawa H, Desban N, Samejima K, Feizbakhsh O, Askin B, Ly T, Earnshaw WC, Ruchaud S. (2019) Plk1-dependent cell cycle-independent furrowing triggered by phosphomimetic mutations of the INCENP STD motif. J Cell Sci. pii: jcs.234401. doi: 10.1242/jcs.234401.

Nguyen TN, Feizbakhsh O, Sfecci E, Baratte B, Delehouzé C, Garcia A, Moulin C, Colas P, Ruchaud S, Mehiri M, Bach S. (2019) Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi. Mar Drugs. 17(10). pii: E569. doi: 10.3390/md17100569.

 Zeinyeh W, Esvan YJ, Josselin B, Baratte B, Bach S, Nauton L, Théry V, Ruchaud S, Anizon F, Giraud F, Moreau P. (2019) Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies. Bioorg Med Chem. 27(10):2083-2089. doi: 10.1016/j.bmc.2019.04.005.

Chassé H., Boulben S., Glippa V., Pontheaux F.,  Cormier P., Morales J. (2019) In vivo analysis of protein translation activity in sea urchin eggs and embryos. Methods in Cell Biol Vol. 151, doi: 10.1016/bs.mcb.2018.10.008

Falaise C, Cormier P, Tremblay R, Audet C, Deschênes JS, Turcotte F, François C, Seger A, Hallegraeff G, Lindquist N, Sirjacobs D, Gobert S, Lejeune P, Demoulin V, Mouget JL. (2019) Harmful or harmless: Biological effects of marennine on marine organisms. Aquat Toxicol. 209:13-25. doi: 10.1016/j.aquatox.2019.01.016.

Chassé H., Boulben S., Cormier P., Morales J. (2019) Translational control of canonical and non-canonical translation initiation factors at the sea urchin egg to embryo transition. Int J Mol Sci. 2019 Feb 1;20(3). pii: E626. doi: 10.3390/ijms20030626.

Motuhi S-E, Feizbakhsh O., Foll-Josselin B., Baratte B., Delehouzé C., Cousseau A., Fant X., Bulinski J.C., Payri C. E., Ruchaud S., Mehiri M., Bach S. (2019) Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides. Mar. Drugs, 17, 93.

Tazarki H., Zeinyeh W., Esvan Y.J., Knapp S., Chatterjee D., Schröder M., Joerger A.C., Khiari J., Josselin B., Baratte B., Bach S., Ruchaud S., Anizon F., Giraud F., Moreau P. (2019). New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis. Eur. J. Med. Chem. 166  304-317.

Oukoloff K., Coquelle N., Bartolini M., Naldi M., Le Guevel R., Bach S., Josselin B., Ruchaud S., Catto M., Pisani L., Denora N., Iacobazzi R.M., Silman I., Sussman J. L., Buron F., Colletier J-P., Jean L., Routier S., Renard P-Y. (2019). Design, Biological Evaluation and X-ray Crystallography of Nanomolar Multifunctional Ligands Targeting Simultaneously Acetylcholinesterase and Glycogen Synthase Kinase-3. Eur J Med Chem. 168:58-77. doi: 10.1016/j.ejmech.2018.12.063.

Mokhtari Brikci-Nigassa N, Nauton L, Moreau P, Mongin O, Duval RE, Picot L, Thiéry V, Souab M, Baratte B, Ruchaud S, Bach S, Le Guevel R, Bentabed-Ababsa G, Erb W, Roisnel T, Dorcet V, Mongin F. (2019) Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest. Bioorg Chem. Oct 10:103347.

Nascimento da Cruz AC, Brondani DJ, I Talo de Santana T, Oliveira da Silva L, da Oliveira Borba EF, de Faria AR, Ferreira Cavalcanti de Albuquerque J, Piessard S, Matos Ximenes R, Baratte B, Bach S, Ruchaud S, Bezerra Mendonça Junior FJ, Bazin MA, Montenegro Rabello M, Hernandes MZ, Marchand P, Gonçalves da Silva T. (2019) Biological evaluation of arylsemicarbazone derivatives as potential anticancer agents displaying kinases inhibition. Pharmaceuticals, 12, 169.

Ziane S., Mazari M.M., Safer A.M., Sad El Hachemi Amar A., Ruchaud S., Baratte B. and Bach S. (2019) Comparison between Conventional and Nonconventional Methods for the Synthesis of Some 2-Oxazolidinone Derivatives and Preliminary Investigation of Their Inhibitory Activity Against Certain Protein Kinases. Russian Journal of Organic Chemistry. Volume 55, Issue 7 (1061–1069).

Khaldoun K., Safer A., Boukabcha N., Dege N., Ruchaud R., Souab M., Bach S., Chouaih A., Saidi-Besbes S. (2019) Synthesis and evaluation of new isatin-aminorhodanine hybrids as PIM1 and CLK1 kinase inhibitors. Journal of Molecular Structure, 2019, Volume: 1192, Pages: 82-90.

Masłyk M, Janeczko M, Martyna A, Czernik S, Tokarska-Rodak M, Chwedczuk M, Foll-Josselin B, Ruchaud S, Bach S, Demchuk OM, Kubiński K. (2019) The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases. Molecules. Jan 2;24(1).

Mignerot L., Nagasato C., Peters A.F., Perrineau M-M., Scornet D., Pontheaux F., Djema W., Badis Y., Motomura T., Coelho S.M., Cock J.M. (2019) Unusual pattern of mitochondrial inheritance in the brown alga Ectocarpus. Mol Biol Evol. 36(12):2778-2789. doi: 10.1093/molbev/msz186.

Lassagne F, Duguépéroux C, Roca C, Perez C, Martinez A, Baratte B, Robert T, Ruchaud S, Bach S, Erb W, Roisnel T, Mongin F. (2019) From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3). Org Biomol Chem 18(1):154-162. doi: 10.1039/c9ob02002k.


Moundoyi H., Demouy J., Lepanse S., Morales J., Sarels B., Cormier P. (2018) Towards multiscale modeling of molecular and biochemical events occurring at fertilization time in sea urchins. In "Marine Organisms as model systems" Editors: M. Kloc and J. Kubiak, Springer (sous presse)

Chassé H., Aubert J., Boulben S., Le Corguillé G., Corre E., Cormier P., Morales J. (2018) Translatome analysis at the egg-to-embryo transition in sea urchin. Nucleic Acids Research, 46(9), 4607–4621.  doi: 10.1093/nar/gky258

Magnani, E., Macchi, F., Mancini, M., Lomazzi, V., Cogliati, S., Pistore, C., Mandruzzato, M., Dock-Bregeon, A.C. and Bonapace, I.M. (2018) UHRF1 regulates CDH1 via promoter associated non-coding RNAs in prostate cancer cells. Biochimica et biophysica acta, 1861, 258-270.

Comai G, Boutet A, Tanneberger K, Massa F, Rocha AS, Charlet A, Panzolini C, Jian Motamedi F, Brommage R, Hans W, Funck-Brentano T, Hrabe de Angelis M, Hartmann C, Cohen-Solal M, Behrens J, Schedl A. (2018) Genetic and molecular insights into genotype-phenotype relationships in osteopathia striata with cranial sclerosis (OSCS) through the analysis of novel mouse Wtx mutant alleles. J Bone Miner Res. doi: 10.1002/jbmr.3387.


Cormier P. (2017) Translation regulator ballet in meiotic spindle. Cell Cycle (Invitation News and Views) doi: 10.1080/15384101.2017.1304732.

Chassé H., Boulben S., Costache V., Cormier P., Morales J. (2017) Analysis of translation using polysome profiling. Nucleic Acids Res. 45(3):e15 doi: 10.1093/nar/gkw907

Mulner-Lorillon O., Chassé H., Morales J., Bellé R., Cormier P. (2017) MAPK/ERK activity is required for the successful progression in mitosis in sea urchin embryos. Dev. Biol. 421(2):194-203 doi: 10.1016/j.ydbio.2016.11.018.

Martinez-Zapien, D., Legrand, P., McEwen, A.G., Proux, F., Cragnolini, T., Pasquali, S. and Dock-Bregeon, A.-C. (2017) The crystal structure of the 5' functional domain of the transcription riboregulator 7SK. Nucleic Acids Res. 45(6), 3568-3579.

Boutet A. (2017) The evolution of asymmetric photosensitive structures in metazoans and the Nodal connection. Mech Dev. 147:49-60. doi: 10.1016/j.mod.2017.09.002.

Boutet A, Comai G, Charlet A, Jian Motamedi F, Dhib H, Bandiera R, Schedl A. (2017) A knock-in mouse line conditionally expressing the tumor suppressor WTX/AMER1. Genesis doi: 10.1002/dvg.23074. [Epub ahead of print]



Cormier P., Chassé H., Cosson B., Mulner-Lorillon O., Morales J. (2016) Translational control in echinoderms: the calm before the storm. In « Evolution of the Protein Synthesis Machinery and its regulation » (Springer publishers). Editors: R. Jagus and G. Hernández. pp.413-434 DOI:10.1007/978-3-319-39468-8_16.

Chassé H, Mulner-Lorillon O, Boulben S, Glippa V, Morales J, Cormier P. (2016)  Cyclin B Translation Depends on mTOR Activity after Fertilization in Sea Urchin Embryos. PLoS One. 10; 11(3): e0150318. doi: 10.1371/journal.pone.0150318.

Jiblaoui A. Barbeau J., Vivès T., Cormier P., Glippa V., Cosson B., Benvegnu T. (2016) Folate-conjugated stealth archaeosomes for the targeted delivery of novel antitumoral peptides. RSC Adv. 6, 75234-75241.

Portier, C. J., Armstrong, B. K., Baguley, B. C., Baur, X., Belyaev, I., Belle, R., .& all, Zhou, S. F. (2016) Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA). J Epidemiol Community Health, 70(8), 741-745. doi: 10.1136/jech-2015-207005.

Picard V, Mulner-Lorillon O, Bourdon J, Morales J, Cormier P, Siegel A and Belle R. (2016) Model of the delayed translation of cyclin B maternal mRNA after sea urchin fertilization. Mol Reprod Dev doi: 10.1002/mrd.22746.

Vandenplas V, Vandeghinste R, Boutet A, Mazan S, Huysseune A. Slow cycling cells in the continuous dental lamina of Scyliorhinus canicula, new evidence for stem cells in sharks (2016) Dev. Biol. 413:39-49 IF 3.1

Bourbigot, S. Dock-Bregeon, A.C., Eberling, P.,  Coutant, J.,  Kieffer, B. and Lebars I. Solution Structure of the 5’-terminal hairpin of the 7SK small nuclear RNA. (2016) RNA 22(12):1844-1858. IF 4.936



Le Grand A, Bouter A, Couturier A, Mulner-Lorillon O, Le Goff X, Chesnel F, Sire O, Le Tilly V. (2015) Investigation of the functional properties and subcellular localization of alpha human and rainbow trout estrogen receptors within a unique  yeast cellular context. J Steroid Biochem Mol Biol. 149:17-26.

Lagadec R, Laguerre L, Menuet A, Amara A, Rocancourt C, Péricard P, Godard BG, Rodicio MC, Rogriguez-Moldes I, Mayeur H, Rougemont Q, Mazan S, Boutet A. (2015) The ancestral role of Nodal signalling in breaking L/R asymmetry in the vertebrate forebrain. Nature Communications  6:6686. IF 11.4

Grande MT, Sánchez-Laorden B, López-Blau C, De Frutos CA, Boutet A, Arévalo M, Rowe RG, Weiss SJ, López-Novoa JM and Nieto MA. Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease (2015) Nature Medicine 21:989-997 IF 27.3



Laurent S., Richard A., Mulner-Lorillon O., Morales J., Flament D., Glippa V., Bourdon J., Gosselin P., Siegel A., Cormier P., Bellé R. (2014) Modelization of the regulation of protein synthesis following fertilization in sea urchin shows require- ment of two processes:  a destabilization of eIF4E:4E-BP  complex and a great stimulation of the 4E-BP-degradation  mechanism, both rapamycin-sensitive.  Frontiers in Genetics, 5:117. doi: 10.3389/fgene.2014.00117.

León K., Boulo. T., Musnier. A., Morales. J., Gauthier. C., Dupuy. L., Heyne. S., Backofen. R., Poupon. A., Cormier. P., Reiter. E. And Crepieux. P. (2014) FSH-induced signaling leads to rapamycin-sensitive phosphorylation of eIF4G at the 5’cap, and also to IRES-dependent translation. J Mol Endocrinol; 52(3):373-82. doi: 10.1530/JME-14-0009.

Masse M, Glippa V, Saad H, Le Bloas R, Gauffeny I, Berthou C, Czjzek M, Cormier P, Cosson B. (2014) An eIF4E-interacting peptide induces cell death in cancer cell lines. Cell Death and Disease, 5:e1500. doi: 10.1038/cddis.2014.457.



Gosselin P., Martineau Y., Morales J., Czjzek M., Gauffeny I., Morin E., Le Corguillé G., Pyronnet S., Cormier P., Cosson B. (2013) Tracking a redefined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E. Nucleic Acids Res. 41(16):7783-7792.



Hidalgo M., Le Bouffant R., Bello V., Buisson N., Cormier P., Beaudry M., Darribère T. (2012). The translational repressor 4E-BP mediates the hypoxia-induced defects in myotome cells. J. Cell Sci 125:3989-4000

Bellé R., Marc J., Morales J., Cormier P., Mulner-Lorillon O. (2012) Letter to the editor : toxicity of roundup and glyphosate. Journal of Toxicology and Environmental Health, Part B, 15:233–237

Costache V., Bilotto S., Laguerre L., Bellé R., Cosson B., Cormier P., Morales J. (2012) Dephosphorylation of eIF2alpha is essential for protein synthesis increase and cell cycle progression after sea urchin fertilization.  Dev Biol. 365 : 303–309

Musnier A., León K., Morales J., Reiter E, Boulo T, Costache V., Vourc'h P., Heitzler D., Oulhen N., Poupon A., Boulben S., Cormier P., Crépieux P. (2012) mRNA-selective translation induced by FSH in primary Sertoli cells. Mol. Endo 26(4):669–680



Bellé, R., Pluchon P-F., Cormier P., Mulner-Lorillon O. (2011) Identification of a new isoform of eEF2 whose phosphorylation is required for completion of cell division in sea urchin embryos. Dev. Biol, 15;350(2):476-83.

Gosselin P., Oulhen N, Jam M, Ronzca J, Cormier P, Czjzek M, Cosson B (2011) The translational repressor 4E-BP called to order by eIF4E: New structural insights by SAXS. Nucleic Acids Research, 39(8):3496-503; doi: 10.1093/nar/gkq1306.