Created 25/02/2017 Updated 11/08/2021

Publications of the team since 2016


  • Beinsteiner Brice, Markov Gabriel V., Erb Stéphane, Chebaro Yasmine, McEwen Alastair G., Cianferani Sarah, Laudet Vincent, Moras Dino and Billas Isabelle M.L. (2021) A structural signature motif enlightens the origin and diversification of nuclear receptors. PLoS Genetics 17, e1009492.
  • Brunet Maéva, de Bettignies Florian, Le Duff Nolwen, Tanguy Gwenn, Davoult Dominique, Leblanc Catherine, Gobet Angélique and Thomas François (2021). Accumulation of detached kelp biomass in a subtidal temperate coastal ecosystem induces succession of epiphytic and sediment bacterial communities. Environmental Microbiology, 23(3), 1638–1655.
  • Burgunter‐Delamare B., Boyen C. & Dittami S.M.* (2021). Effect of essential oil- and iodine treatments on the bacterial microbiota of the brown alga Ectocarpus siliculosus. Journal of Applied Phycology, 33, 459–470. doi:10.1007/s10811-020-02286-y.
  • Creis Bendelac Emeline, Delage Ludovic, Vallet Laurent, Leblanc Catherine, Kruse Inken, Ar Gall Erwan*, Weinberger Florian and Potin Philippe (2021). Induction of Phlorotannins and Gene Expression in the Brown Macroalga Fucus vesiculosus in Response to the Herbivore Littorina littorea. Marine Drugs, 19, 185.
  • Simon M. Dittami, Enrique Arboleda, Jean-Christophe Auguet, Arite Bigalke, Enora Briand, Paco Cárdenas, Ulisse Cardini, Johan Decelle, Aschwin Engelen, Damien Eveillard, Claire M.M. Gachon, Sarah Griffiths, Tilmann Harder, Ehsan Kayal, Elena Kazamia, Francois H. Lallier, Mónica Medina, Ezequiel M. Marzinelli, Teresa Morganti, Laura Núñez Pons, Soizic Pardo, José Pintado Valverde, Mahasweta Saha, Marc-André Selosse, Derek Skillings, Willem Stock, Shinichi Sunagawa, Eve Toulza, Alexey Vorobev, Catherine Leblanc and Fabrice Not (2021). A community perspective on the concept of marine holobionts: state-of-the-art, challenges, and future directions. PeerJ, 9, e10911.
  • Fort, A., McHale, M., Cascella, K., Potin, P., Perrineau, M., Kerrison, P. D., Costa, E., Calado, R., Domingues, M. D. R., Costa Azevedo, I., Sousa‐Pinto, I., Gachon, C., Werf, A., Visser, W., Beniers, J. E., Jansen, H., Guiry, M. D., & Sulpice, R. (2021). Exhaustive reanalysis of barcode sequences from public repositories highlights ongoing misidentifications and impacts taxa diversity and distribution. Molecular Ecology Resources. doi/10.1111/1755-0998.13453.
  • Fort, A., Linderhof, C., Coca-Tagarro, I., Inaba, M., McHale, M., Cascella, K., Potin, P., Guiry, M. D., & Sulpice, R. (2021). A sequencing-free assay for foliose Ulva species identification, hybrid detection and bulk biomass characterisation. Algal Research, 55, 102280.
  • Jean Girard, Goulven Lanneau, Ludovic Delage, Cédric Leroux, Arnaud Belcour, Jeanne Got, Jonas Collén, Catherine Boyen, Anne Siegel, Simon M Dittami, Catherine Leblanc, Gabriel V. Markov (2021). Semi-quantitative targeted GC-MS profiling supports a late side-chain reductase cycloartenol-to-cholesterol biosynthesis pathway in brown algae. Frontiers in Plant Science, section Marine and Freshwater Plants, 12, 648426.
  • Elham Karimi, Enora Geslain, Arnaud Belcour, Clémence Frioux, Méziane Aite, Anne Siegel, Erwan Corre, Simon M Dittami (2021). Robustness analysis of metabolic predictions in algal microbial communities based on different annotation pipelines. PeerJ, 9, e11344.
  • Lebeau Diane, Leroy Nathalie, Doizi Denis, Wu Ting-Di, Guerquin-Kern Jean-Luc, Perrin Laura, Ortega Richard, Voiseux Claire, Fournier Jean-Baptiste, Potin Philippe, Fievet Bruno, Leblanc Catherine (2021). Mass spectrometry – based imaging techniques for iodine-127 and iodine-129 detection and localization in the brown alga Laminaria digitata. Journal of Environmental Radioactivity, 231, 106552. doi: 10.1016/j.jenvrad.2021.106552.
  • Monteiro Catia, Li Huiru, Diehl Nora, Bischof Kai, Heinrich Sandra, Collén Jonas & Bartsch Inka (2021) Modulation of physiological performance by temperature and salinity in the sugar kelp Saccharina latissima. Phycological Research, 69, 48-57.
  • Paix Benoît, Vieira Christophe, Potin Philippe, Leblanc Catherine, De Clerck Olivier, Briand Jean-François, Culioli Gérald (2021). French Mediterranean and Atlantic populations of the brown algal genus Taonia (Dictyotales) display differences in phylogeny, surface metabolomes and epibacterial communities. Algal Research, 59, 102452.
  • Jose Robla, J. García-Hierro, F. Alguacil, S.M. Dittami, D. Marie, E. Villa, E. Deragon, D. Guillebault, G. Mengs, L.K. Medlin (2021). Determination of the Efficiency of Filtration of Cultures from Microalgae and Bacteria using Hollow Fiber Filters. Environ. Sci.: Water Res. Technol.
  • Xing Qikun, Rousvoal Sylvie, Leblanc Catherine (2021). Transcriptome-wide identification and evaluation of optimal reference genes for RT-qPCR expression analysis of Saccharina latissima responses to biotic and abiotic stress. Journal of Applied Phycology, 33:617–627.


  • Belcour A.; Girard J.; Aite M.; Delage L.; Trottier C.; Marteau C.; Leroux C.; Dittami S. M.; Sauleau P.; Corre E.; Nicolas J.; Boyen C.; Leblanc C.; Collén J.; Siegel A. & Markov G. V.* (2020). Inferring biochemical reactions and metabolite structures to cope with metabolic pathway drift. iScience, 23(2), 100849.
  • de Bettignies F*, Dauby P, Thomas F, Gobet A, Delage L, Bohner O, Loisel S, Davoult D (2020). Degradation dynamics and processes associated with the accumulation of Laminaria hyperborea (Phaeophyceae) kelp fragments: an in situ experimental approach. Journal of Phycology, 56 (6), 1481-1492.
  • Burgunter-Delamare Bertille, KleinJan Hetty, Frioux Clemence, Fremy Enora, Wagner Margot, Corre Erwan, Le Salver Alicia, Leroux Cédric, Leblanc Catherine, Boyen Catherine, Siegel Anne, M Dittami Simon* (2020). Metabolic complementarity between a brown alga and associated cultivable bacteria provide indications of beneficial interactions. Frontiers in Marine Science, section Marine Ecosystem Ecology, 7, 85. doi: 10.3389/fmars.2020.00085.
  • Canonge J, Philippot M, Leblanc C, Potin P, Bodin M. (2020). Impedance flow cytometry allows the early prediction of embryo yields in wheat (Triticum aestivum L.) microspore cultures. Plant Science, 300: 110586.
  • Simon M. Dittami*, Erwan Corre, Loraine Brillet-Guéguen, Agnieszka P. Lipinska, Noé Pontoizeau, Agnieszka P. Lipinska, Meziane Aite, Komlan Avia, Christophe Caron†, Chung Hyun Cho, Jonas Collén, Alexandre Cormier, Ludovic Delage, Sylvie Doubleau, Clémence Frioux, Angélique Gobet, Irene González-Navarrete, Agnès Groisillier, Cécile Hervé, Didier Jollivet, Hetty KleinJan, Catherine Leblanc, Xi Liu, Dominique Marie, Gabriel V. Markov, André E. Minoche, Misharl Monsoor, Pierre Pericard, Marie-Mathilde Perrineau, Akira F. Peters, Anne Siegel, Amandine Siméon, Camille Trottier, Hwan Su Yoon, Heinz Himmelbauer, Catherine Boyen, Thierry Tonon (2020). The genome of Ectocarpus subulatus – a highly stress-tolerant brown alga. Marine Genomics, 52, 100740.
  • Dittami, S.M.*, Peters, A.F., West, J.A., Cariou, T., KleinJan, H., Burgunter‐Delamare, B., Prechoux, A., Egan, S. & Boyen, C. (2020). Revisiting Australian Ectocarpus subulatus (Phaeophyceae) From the Hopkins River: Distribution, Abiotic Environment, and Associated Microbiota. J. Phycol. 56, 719–29.
  • Fort A, McHale M, Cascella K, Potin P, Usadel B, Guiry MD, Sulpice R (2020). Large foliose Ulva species show considerable genetic diversity among European species, and the rare occurrence of inter-specific hybrids. J. Phycol. 57, 219-233.
  • Frioux, C., Dittami, S.M. & Siegel, A. (2020). Using automated reasoning to explore the metabolism of unconventional organisms: a first step to explore host–microbial interactions. Biochem. Soc. Trans. 48, 901–13.
  • Karimi, E., Geslain, E., KleinJan, H., Tanguy, G., Legeay, E., Corre, E., & Dittami, S. M. (2020). Genome Sequences of 72 Bacterial Strains Isolated from Ectocarpus subulatus: A Resource for Algal Microbiology. Genome Biology and Evolution, 12(1), 3647–3655.
  • Lipinska A, Collén J, Krueger‑Hadfield SA, Theo Mora T & Ficko‑Blean E (2020) To gel or not to gel: differential expression of carrageenan‑related genes between the gametophyte and tetasporophyte life cycle stages of the red alga Chondrus crispus. Scientific reports 10, 11498.
  • Mat AM, Sarrazin J, Markov GV, Apremont V, Dubreuil C, Eche C, Fabioux C, Klopp C, Sarradin PM, Tanguy A, Huvet A, Matabos M. (2020). Biological rhythms in the deep-sea hydrothermal mussel Bathymodiolus azoricus. Nature Communications, 11, 3454.
  • Roussel S., Poitevin P., Day R., Legrand F., Stiger-Pouvreau V., Leblanc C. and Huchette S. (2020). Foraging strategy of a large marine herbivore, Haliotis tuberculata: a generalist that prefers a mixed diet, but with consistent individual foraging activity. Ethology, 126, 716–726.
  • Thomas François, Dittami Simon M., Brunet Maéva, Le Duff Nolwen, Tanguy Gwenn, Leblanc Catherine and Gobet Angélique (2020). Evaluation of a new primer combination to minimize plastid contamination in 16S rDNA metabarcoding analyses of alga-associated bacterial communities. Environmental Microbiology Reports, 12(1), 30–37.
  • Claire Vigor, Camille Oger, Guillaume Reversat, Amandine Rocher, Bingqing Zhou, Amandyne Linares-maurizi, Alexandre Guy, Valérie Bultel-Poncé, Jean-Marie Galano, Joseph Vercauteren, Thierry Durand, Philippe Potin, Thierry Tonon, Catherine Leblanc (2020). Isoprostanoid Profiling of Marine Microalgae. Biomolecules, 10, 1073.
  • Yao H, Scornet D, Peters AF, Jam M, Hervé C, Potin P, Coelho SM, Cock JM. (2020). Production and Bioassay of a Diffusible Factor That Induces Gametophyte-to-Sporophyte Developmental Reprogramming in The Brown Alga Ectocarpus. Bio-protocol, 10(18), e3753.


  • Bernard M., Rousvoal S., Collet N., Le Goff T., Jacquemin B., Peters, A.F., Potin, P. & Leblanc C. (2019). A highly prevalent filamentous algal endophyte in natural populations of the sugar kelp Saccharina latissima is not detected during cultivation in Northern Brittany. Aquatic Living Resources, 32, 21.
  • Laetitia Guillot, Ludovic Delage, Alain Viari, Yves Vandenbrouck, Emmanuelle Com, Andrés Ritter, Régis Lavigne, Dominique Marie, Pierre Peterlongo, Philippe Potin and Charles Pineau (2019). Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes. BMC Genomics 20, 56.
  • Laudet V, Markov GV. (2019). Evolution of Hormonal Mechanisms. In Ilpo Huhtaniemi and Luciano Martini (Eds.) Encyclopedia of Endocrine Diseases, Second Edition, vol 1, pp. 16-22. Oxford: Academic Press.
  • Cátia Marina Machado Monteiro, Huiru Li, Kai Bischof, Inka Bartsch, Klaus Ulrich Valentin, Erwan Corre, Jonas Collén, Lars Harms, Gernot Glöckner and Sandra Heinrich (2019). Is geographical variation driving the transcriptomic responses to multiple stressors in the kelp Saccharina latissima? BMC Plant Biology 19, 513.
  • Monteiro C, Heinrich S, Bartsch I, Valentin K, Corre E, Collén J, Harms L, Glöckner G & Bischof K (2019) Temperature modulates sex-biased gene expression in the gametophytes of the kelp Saccharina latissima. Frontiers Marine Science, 6, 769.
  • Nègre Delphine, Aite Méziane, Belcour Arnaud, Frioux Clémence, Brillet−Guéguen, Loraine, Liu Xi, Bordron Philippe, Godfroy Olivier, Lipinska Agnieszka P., Leblanc Catherine, Siegel Anne, Dittami Simon M., Corre Erwan and Markov Gabriel V.* (2019). Genome-Scale Metabolic Networks Shed Light on the Carotenoid Biosynthesis Pathway in the Brown Algae Saccharina japonica and Cladosiphon okamuranus. Antioxidants, 8 (11), 564.
  • Roussel S., Caralp C., Leblanc C., Le Grand F., Stiger V., Coulombet C., Le Goïc N. &, Huchette S. (2019). Impact of nine macroalgal diets on growth and initial reproductive investment in juvenile abalone Haliotis tuberculata. Aquaculture, 513, 734385.
  • Saha, M Elisa Berdalet, Ylenia Carotenuto, Patrick Fink, Tilmann Harder, Potin P. et al.. (2019). Using chemical language to shape future marine health. Frontiers in Ecology and the Environment, Ecological Society of America, 17(9), 530-537.
  • Teng L, Fan X, Nelson DR, Han W, Zhang X, Xu D, Renault H, Markov GV, Ye N. (2019). Diversity and evolution of cytochromes P450 in Stramenopiles. Planta, 249, 647-661.


  • Aite M, Chevallier M, Frioux C, Trottier C, Got J, Paz Cortés M, Loira N, Carrier G, Dameron O, Guillaudeux N, Latorre M, Mendoza S, Markov GV, Maass A, Siegel A. (2018) Traceability, reproducibility and wiki-exploration for “à-la-carte” reconstructions of genome-scale metabolic models. Plos Comput Biol, 14, e1006146.
  • Bernard M., Rousvoal S., Jacquemin B., Ballenghien M., Peters A.F. and Leblanc C. (2018). qPCR-based relative quantification of the brown algal endophyte Laminarionema elsbetiae in Saccharina latissima: variation and dynamics of host – endophyte interactions. Journal of Applied Phycology, 30, 2901–2911.
  • Bernard M., Strittmatter M., Murua P., Heesch S., Cho G. Y., Leblanc C., Peters A. F. (2018). Diversity, biogeography and host specificity of kelp endophytes with a focus on the genera Laminarionema and Laminariocolax (Ectocarpales, Phaeophyceae). European Journal of Phycology, 54(1), 39-51.
  • Falcke JM, Bose B, Artyukhin AB, Roedelsperger C, Markov GV, Yim JJ, Grimm D, Claassen M, Panda O, Baccile JA, Jolic D, Schroeder FC, Sommer RJ. (2018) Linking Genomic and Metabolomic Natural Variation Uncovers Nematode Pheromone Biosynthesis. Cell Chemical Biology, 25, 787-796.
  • Gobet A., Mest L., Perennou M., Dittami S., Caralp C., Coulombet C., Huchette S., Roussel S., Michel G. and Leblanc C. (2018). Seasonal and diet-driven patterns of a core microbiota associated to macroalgal digestion in a generalist marine herbivore. Microbiome, 6, 60.
  • Markov G., Girard J., Laudet V., Leblanc C. (2018). Hormonally active phytochemicals from macroalgae: a largely untapped source of ligands for deorphanizing nuclear receptors in emerging marine animal models. General and Comparative Endocrinology, 265, 41-45.
  • Khalturin K, Billas IML, Chebaro Y, Reitzel AM, Tarrant AM, Laudet V, Markov GV. (2018). NR3E receptors in cnidarians: A new family of steroid receptor relatives extends the possible mechanisms for ligand binding. J Steroid Biochem Mol Biol 184, 11-19.
  • Radlow M., Czjzek M., Jeudy A., Dabin J., Delage L., Leblanc C. and Hartung J. (2018). Insights from X-Ray-Diffraction and Density Functional Theory Reveal Mode of Vanadate Binding to Homohexameric Bromoperoxidase II from Ascophyllum nodosum and Mechanism of Bromide Oxidation. ACS Chemical Biology, 13 (5), 1243-1259.
  • Teng, L., Han, W., Fan, X., Xu, D., Zhang, X., Dittami, S.M. and Ye, N. (2017) Evolution and Expansion of the Prokaryote-Like Lipoxygenase Family in the Brown Alga Saccharina japonica. Front. Plant Sci., 8.
  • Tonon AP, Zaini PA, dos Reis Falcão V, Cabral Oliveira M, Collén J, Boyen C & Colepicolo P (2018) Gracilaria tenuistipitata (Rhodophyta) tolerance to cadmium and copper exposure observed through gene expression and photosynthesis analyses. Journal of Applied Phycology, 30, 2129–2141.
  • Vigor C., Reversat G.; Rocher A.; Oger C.; Galano J.-M.; Vercauteren J.; Durand T.; Tonon T.; Leblanc C.; Potin P. (2018). Isoprostanoids quantitative profiling of marine red and brown macroalgae. Food Chemistry, 268 (1), 452-462.


  • Brawley SH, Blouin NA, Ficko-Blean E, Wheeler GL, Lohr M, Goodson HV, Jenkins JW, Blaby-Haash CE, Helliwell KE, Chan CX, Marriage T, Bhattacharya D, Klein AS, Badis Y, Brodie J, Cao Y, Collén J, Dittami SM, Gachon CMM, Green BR, Karpowicz S, Kim JW, Kudahl UJ, Lin S, Michel G, Mittag M, Olson BJSC, Pangilinan J, Peng Y, Qiu H, Shu S, Singer JT, Smith AG, Sprecher BN, Wagner V, Wang W, Wang Z-Y, Yan J, Yarish C, Zäuner-Riek S, Zhuang YY, Zou Y, Lindquist EA, Grimwood J, Barry K, Rokhsar DS, Schmutz J, Stiller JW, Grossman AR, Prochnik SE. (2017) Insights into the red algae from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta). Proceedings of the National Academy of Science, 114 (31), E6361-E6370.
  • Dittami SM and Corre E (2017). Detection of bacterial contaminants and hybrid sequences in the genome of the kelp Saccharina japonica using Taxoblast. PeerJ, 5, e4073.
  • Dittami SM, Heesch S, Olsen JL, Collén J. (2017). Transitions between marine and freshwater environments provide new clues about the origins of multicellular plants and algae. Journal of Phycology, 53, 731–745.
  • Ilangumaran G, Stratton G, Ravichandran S, Shukla PS, Potin P, Asiedu S, Prithiviraj B. (2017) Microbial Degradation of Lobster Shells to Extract Chitin Derivatives for Plant Disease Management. Front Microbiol, 8, 781.
  • KleinJan H, Jeanthon C, Boyen C, Dittami SM (2017) Exploring the Cultivable Ectocarpus Microbiome. Frontiers in Microbiology, 8, 2456.
  • Prigent S, Frioux C, Dittami SM, Thiele S, Larhlimi A, Collet G, Gutknecht F, Got J, Eveillard D, Bourdon J, Plewniak F, Tonon T, Siegel A. (2017). Meneco, a Topology-Based Gap-Filling Tool Applicable to Degraded Genome-Wide Metabolic Networks (C Kaleta, Ed.). PLOS Computational Biology 13, e1005276.
  • Ritter A., Cabioch L., Brillet-Guéguen L., Corre E., Cosse A., Dartevelle L., Duruflé H., Fasshauer C., Goulitquer S., Thomas F., Correa J. A., Potin P, Faugeron S. and Leblanc C. (2017). Herbivore-induced chemical and molecular responses of the kelps Laminaria digitata and Lessonia spicata. Plos One, 12(3), e0173315.
  • Wells ML, Potin P, Craigie JS, Raven JA, Merchant S, Helliwell KE, Smith AG, Camire ME, Brawley SH, (2017). Algae as nutritional and functional food sources: revisiting our understanding. Journal of Applied Phycology, 29, 949-982.


  • Barbeyron T, Thomas F, Barbe V, Teeling H, Schenowitz C, Dossat C, Goesmann A, Leblanc C, Glöckner FO, Czjzek M, Amann R and Michel G. (2016) Habitat and taxon as driving forces of carbohydrate catabolism in marine heterotrophic bacteria: example of the model algae-associated bacterium Zobellia galactanivorans. Environmental Microbiology, 18, 4610-4627.
  • Bennke CM, Krüger K, Kappelmann L, Huang S, Gobet A, Schüler M, Barbe V, Fuchs BM, Michel G, Teeling H, Amann RI (2016). Polysaccharide Utilization Loci of Bacteroidetes from two contrasting open ocean sites in the North Atlantic. Environmental Microbiology, 18, 4456-4470.
  • Dittami SM, Duboscq-Bidot L, Perennou M, Gobet A, Corre E, Boyen C, Tonon T. 2016. Host–microbe interactions as a driver of acclimation to salinity gradients in brown algal cultures. The ISME Journal 10, 51–63.
  • Groisillier A. and Tonon T. (2016) Determination of Mannitol-1-phosphate dehydrogenase Activity from Ectocarpus sp. Bio-protocol 6 (21), e1982.
  • Groisillier A. and Tonon T. (2016). Determination of Recombinant Mannitol-1-phosphatase Activity from Ectocarpus sp. Bio-protocol 6(16), e1896.
  • Leroux B.J.G., Potin P., Larher F.R., Bodin M. (2016) Enhancement of embryo yield from isolated microspores of Brassica napus by early iron starvation, Plant Biotechnology Reports. 10, 463-486.
  • Olsen JL, Rouzé P, Verhelst B, Lin Y-C, Bayer T, Collen J, Dattolo E, De Paoli E, Dittami SM, Maumus F, Michel G, Kersting A, Lauritano C, Lohaus R, Töpel M, Tonon T, Vanneste K, Amirebrahimi M, Brakel J, Boström C, Chovatia M, Grimwood J, Jenkins JW, Jueterbock A, Mraz A, Stam WT, Tice H, Bornberg-Bauer E, Green PJ, Pearson GA, Procaccini G, Duarte CM, Schmutz J, Reusch TBH, Van de Peer Y. 2016. The genome of the seagrass Zostera marina reveals angiosperm adaptation to the sea. Nature 530, 331–335.
  • Potin P, Nicolè F & Thomas OP (2016). Metabolomic contributions to chemical ecology. Chapter 7. In New Advances in Chemical Ecology (A.-G. Bagnères and M. Hossaert McKey, eds), Coll. ISTE-Wiley, p.139-160.
  • Prado S., Leblanc C. and Rebuffat S. (2016) Microbiome and chemical ecology. Chapter 4. In New Advances in Chemical Ecology (A.-G. Bagnères and M. Hossaert McKey, eds), Coll. ISTE-Wiley, p.71-94.
  • Rousvoal S, Bouyer B, López-Cristoffanini C, Boyen C & Collén J (2016) Mutants swarms of a totivirus-like entity are present in the red macroalga Chondrus crispus and have been partially transferred to the nuclear genome. Journal of Phycology 52, 493-504
  • Tapia JE, González B, Goulitquer S, Potin P, Correa JA. (2016) Microbiota Influences Morphology and Reproduction of the Brown Alga Ectocarpus sp. Front Microbiol. 27, 197.