Photo Gabriel Markov

Gabriel MARKOV

Chargé de recherche CNRS
Co-head of the ABIE team and scientific manager of the Metabomer platform

I investigate metabolic pathway evolution, integrating information about the evolution of single enzymes with the distribution of metabolites accross lineages. This led me to develop methods to tackle directly the evolution of pathways at that level of abstraction. I am strongly interested about eukaryotic metabolic pathways for which there is a significant amount of detailed biological knowledge, such as those producing signaling molecules.

Publications

Metagenome-scale metabolic modelling for the characterization of cross-feeding interactions in freshwater cyanobacteria-associated microbial communities

Juliette Audemard, Nicolas Creusot, Julie Leloup, Charlotte Duval, Sébastien Halary, et al.. Metagenome-scale metabolic modelling for the characterization of cross-feeding interactions in freshwater cyanobacteria-associated microbial communities. JOBIM 2025 - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2025, Bordeaux, France. ⟨hal-05281552⟩

Methods for a species-specific genome-scale metabolic model designed for eukaryotes and applied to the Ascophyllum nodosum macroalga

Pauline Hamon-Giraud, Benoît Bergk Pinto, Jeanne Got, Coralie Rousseau, Erwan Corre, et al.. Methods for a species-specific genome-scale metabolic model designed for eukaryotes and applied to the Ascophyllum nodosum macroalga. JOBIM 2025 - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2025, Bordeaux, France. pp.109-117. ⟨hal-05374724⟩

Cholesterol and sterols in molluscan endocrinology: past, present, future

István Fodor, Gabriel V. Markov, Luis Alfonso Yañez-Guerra, Károly Elekes, Edit Pollák, et al.. Cholesterol and sterols in molluscan endocrinology: past, present, future. Frontiers in Endocrinology, 2025, 16, ⟨10.3389/fendo.2025.1627166⟩. ⟨hal-05405123⟩

Sterol biosynthesis and phytosterol bioconversion in Crassostrea gigas larvae: new evidence from mass-balance feeding studies

Fiz da Costa, Margaux Mathieu-Resuge, Fabienne Le Grand, Claudie Quéré, Gabriel V. Markov, et al.. Sterol biosynthesis and phytosterol bioconversion in Crassostrea gigas larvae: new evidence from mass-balance feeding studies. Biochimie, 2025, 239, Part A, pp.51-59. ⟨10.1016/j.biochi.2025.05.005⟩. ⟨hal-05405141⟩

Differential impact of copper stress in two Ectocarpales: metabolic disruption and defensive signaling in the free-living Ectocarpus sp7 and the endophytic Laminarionema elsbetiae

Maëlle Zonnequin, Marine Vallet, Ludovic Delage, Georg Pohnert, Catherine Leblanc, et al.. Differential impact of copper stress in two Ectocarpales: metabolic disruption and defensive signaling in the free-living Ectocarpus sp7 and the endophytic Laminarionema elsbetiae. Biochimie, 2025, 239, pp.93-102. ⟨10.1016/j.biochi.2025.10.006⟩. ⟨hal-05405218⟩

Evolution of hormonal mechanisms

Brice Beinsteiner, Isabelle M.L. Billas, Dino Moras, Vincent Laudet, Gabriel V. Markov. Evolution of hormonal mechanisms. Ilpo Huhtaniemi, Luciano Martini. Encyclopedia of Endocrine Diseases, 3rd edition, Elsevier, 2025, 9780128122006. ⟨10.1016/B978-0-443-13825-6.00251-X⟩. ⟨hal-05405253⟩