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Cecile Herve

Cécile HERVE

Directrice de recherche CNRS
Unité(s) de recherche
Laboratoire de Biologie Intégrative des Modèles Marins
Equipe(s)
Team BAG - Brown Algal Glycans
Plateforme(s)
SeaProbes

I am interested in seaweed glycobiology. Part of my work is dedicated in unravelling the cell-wall architecture of brown algae, with a specific focus on the alginates and fucans/fucoidans polysaccharides. I develop and distribute monoclonal antibodies to the global community for screening and imaging cell-wall glycans from brown algae. I am currently strongly involved in pioneering studies on alginate and fucan biosynthetic pathways.

I use a range of techniques from molecular to biological sciences to gain fundamental insights into how brown algae function. My research is driven by 2 perspectives:

  1. understanding molecular processes critical to the physiology of brown algae, through an evolutive angle, and with the development of new tools and pipelines
  2. translating this knowledge to better understand kelp resilience in the wild and in offering new avenues for the bioprospecting of algal biomass from off-shore seaweed farms. 

Positions

2025 – now; Directrice de recherche, Brown Algal Glycans team, CNRS, SB Roscoff
2010-2025; Chargée de recherche, Marine Glycobiology team, CNRS, SB Roscoff
2009-2010; Post-doctoral fellow, Marine Glycobiology team, CNRS, SB Roscoff, France
2007-2009; Post-doctoral fellow, JP Knox- Cell Wall team, University of Leeds, UK
2006-2007; Post-doctoral fellow, Marine Glycobiology team, CNRS, SB Roscoff, France
2002-2006; PhD student, Functional Genomics team, CNRS, SB Roscoff, France

Education and key qualifications

2022; Habilitation to Direct Research (HDR), ED227 Sorbonne University, France
2006; PhD in Plant biology & Phycology, University of Rennes 1, France
2002; Master Degree in Fisheries Sciences, ENSA, Rennes, France
2001; Bachelor Degree in Agronomy, ENITA, Bordeaux, France
1998; Technical degree in Biochemistry, LEGTA, Rezé, France
 

Publications

Exploration of the extracellular matrix of the red alga Chondrus crispus reveals unprecedented insights into carrageenan structures

David Ropartz, Adrien Lissarrague, Murielle Jam, Diane Jouanneau, Bastien Annic, et al.. Exploration of the extracellular matrix of the red alga Chondrus crispus reveals unprecedented insights into carrageenan structures. Carbohydrate Polymers, 2025, 348, pp.122737. ⟨10.1016/j.carbpol.2024.122737⟩. ⟨hal-04734206⟩

Spatiotemporal regulation of alginate sub-structures at multiple scales revealed by monoclonal antibodies

Catherine T Jones, Cassie Bakshani, Ieva Lelenaite, Jozef Mravec, Stjepan Krešimir Kračun, et al.. Spatiotemporal regulation of alginate sub-structures at multiple scales revealed by monoclonal antibodies. The Cell Surface, 2025, 13, pp.100136. ⟨10.1016/j.tcsw.2024.100136⟩. ⟨hal-05356727⟩

Candidate genes involved in biosynthesis and degradation of the main extracellular matrix polysaccharides of brown algae and their probable evolutionary history

Lisa Mazéas, Ahlem Bouguerba-Collin, J. Mark Cock, France Denoeud, Olivier Godfroy, et al.. Candidate genes involved in biosynthesis and degradation of the main extracellular matrix polysaccharides of brown algae and their probable evolutionary history. BMC Genomics, 2024, 25 (1), pp.950. ⟨10.1186/s12864-024-10811-3⟩. ⟨hal-04734202⟩

Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems

France Denoeud, Olivier Godfroy, Corinne Cruaud, Svenja Heesch, Zofia Nehr, et al.. Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems. Cell, 2024, 187 (24), pp.6943-6965. ⟨10.1016/j.cell.2024.10.049⟩. ⟨hal-04794231⟩

Heterologous Expression and Biochemical Characterization of a New Chloroperoxidase Isolated from the Deep-Sea Hydrothermal Vent Black Yeast Hortaea werneckii UBOCC-A-208029

Bastien Cochereau, Yoran Le Strat, Qiaolin Ji, Audrey Pawtowski, Ludovic Delage, et al.. Heterologous Expression and Biochemical Characterization of a New Chloroperoxidase Isolated from the Deep-Sea Hydrothermal Vent Black Yeast Hortaea werneckii UBOCC-A-208029. Marine Biotechnology, 2023, 25 (4), pp.519-536. ⟨10.1007/s10126-023-10222-7⟩. ⟨hal-04241644⟩

Assembly and synthesis of the extracellular matrix in brown algae

Lisa Mazéas, Rina Yonamine, Tristan Barbeyron, Bernard Henrissat, Elodie Drula, et al.. Assembly and synthesis of the extracellular matrix in brown algae. Seminars in Cell and Developmental Biology, In press, 134, pp.112-124. ⟨10.1016/j.semcdb.2022.03.005⟩. ⟨hal-03627114⟩

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