2021-2026 ERC PROJECT GRANT (DYNAMIC), PI: F. LE ROUX
The aim of this project is to shed light on key ecological and evolutionary processes underlying phage-bacteria dynamics in the marine environment. An oyster bacterial pathogen, V. crassostreae and its infecting phages will be used as model system to investigate the molecular bases and evolution of phage infections in nature
2016 – 2020 ANR project grant (REVENGE), 502 k€, PI: F. Le Roux.
The aim of this project is to investigate the evolution of vibrio virulence in relation to the oyster as a host and phages as predators. This will allow to determine whether i) pathogenic genotypes of Vibrio emerge in areas experiencing mass mortalities; ii) Vibrio and oysters co-evolve; iii) Vibrio-phage infection networks are more highly connected in co-occurring phages and hosts.
2014 – 2018 ANR project grant (OPOPOP), 362k€, PI: F. Le Roux.
The aim of this project was to investigate the partitioning of vibrios into ecologically distinct populations at fine environmental and genotypic resolution scales. This allowed us to determine (i) from what types of microhabitats oyster pathogens emerge, (ii) how populations shift during disease events, and (iii) what genomic features correlate to differential microhabitat association (including pathogenesis)
2012 – 2016 ANR project grant (VIBRIOGEN), ANR, 539K€, PI: F. Le Roux.
The aim of this project was to investigate virulence as an emerging property of strains or population in vibrios infecting marine invertebrates. Virulence was viewed not only as the result of acquiring new genetic resources through genomic plasticity but also, and foremost, through the interactions between vibrios, be it at the level of the interaction between replicons or between strains within the population
2011 – 2012 Starting grant from Bretagne region (VIBRIGEN), 2011-12, 50,000 euros, PI: F. Le Roux
This project funded the setting up of my group as new team of the Marine Station of Roscoff and first experiments assessing vibrio (i) as clonal lineage that infect shrimp; and (ii) populations that infect oysters.