Post Doc

Sebastian Metz

Research interests

My research project aims to understand the role of the pathobiome (i.e. the symbiont community related to a disease) during the infection process of a protist parasite (Perkinsus olseni) in the Manila Clams population. To tackle this, I will integrate different molecular approaches to study the diversity and functioning of the pathobiome and its interactions with the host and the parasite. This fundamental research will allow us better understand the biotic factors that influence the virulence of the parasite.

 

  • Host - parasites - pathobiome system functioning
  • Diversity and function of Protists
  • Microorganisms interactions
  • Molecular phylogeny

 

Educational Background

  • 2020 - 2021: Post-doc (14 months) “Phenotypic plasticity of an exotic and generalist parasite Perkinsus olseni in Bay of Brest”. UMR6539 LEMAR - Laboratoire des sciences de l'Environnement MARin. Plouzané (29280), France.
  • 2015 - 2020: PhD in molecular biology and biotechnology. National University of San Martín. Laboratory of Aquatic Ecology, National Institute of Chascomús (INTECH), Argentina. Dissertation: “Diversity, distribution and composition of picoeukaryote algae in freshwater environments”.
  • 2010 - 2015: Licenciado (Similar to MSc) in Bioinformatics. National University of Entre Ríos (UNER), Argentina. Dissertation: "Computational study of enzymatic hydrolysis of three anti-HIV prodrugs''.

 

Main current  Research Projects

2022-2025. “PANIC: Diversity and role of the PAthobiome in infection by an iNvasive parasitIC protist in clam populations” PI Dr. Chambouvet ANR - JCJC PANIC.

2020-2022. “Phenotypic plasticity of an exotic and generalist parasite Perkinsus olseni in Bay of Brest” PI Dr. Chambouvet Aurélie. SAD région Bretagne - Accueil de chercheuses et chercheurs internationaux en post-doctorat, France.

2021-2022. “Deep learning Meets biodiversity: unveiling the Microbiome of a Mega-river”. PI: Dr. M Devercelli. Laboratory of Plankton. INALI. Santa Fe, Argentina. Financed by National Geographic Society (grant reference number NGS-85578T-21).

 

Publications

2021- Itoïz, S., Metz, S., Derelle, E., Reñé, A., Garcés, E., Bass, D., Soudant, P. and Chambouvet, A. Emerging parasitic protists: the case of Perkinsea. Frontiers Microbiology. https://doi.org/10.3389/fmicb.2021.735815.

2021- Metz, S., Huber, P., Accattatis, V., Lopes dos Santos, A., Bigeard, E., Unrein, F., Chambouvet, A., Not, F., Lara E. and Devercelli, M. Freshwater Protists: unveiling the unexplored in a large floodplain system. Environmental Microbiology. https://doi.org/10.1111/1462-2920.15838

2021-   Fermani, P., Metz, S., Balagué, V., Descy, J. P., Morana, C., Logares, R., Massana, R. and Sarmento, H. (2021). Microbial eukaryote assemblages and potential novel diversity in four tropical East African Great Lakes. FEMS Microbiology Ecology, 97(9), fiab114.

2020- Huber, P., Metz, S., Unrein, F., Mayora, G., Sarmento, H. and Devercelli, M., 2020. Environmental heterogeneity determines the ecological processes that govern bacterial metacommunity assembly in a floodplain river system. The ISME Journal, 14(12), pp.2951-2966.

2020- Accattatis, V., Piccini, C., Huber, P., Metz, S., Rueda, E. and Devercelli, M., 2020. Identifying invaders: the case of Ceratium furcoides (Gonyaulacales, Dinophyceae) in South America. Journal of phycology, 56(5), pp.1362-1366.

2020- Berman, M.C., Llames, M.E., Minotti, P., Fermani, P., Quiroga, M.V., Ferraro, M.A., Metz, S. and Zagarese, H.E., 2020. Field evidence supports former experimental claims on the stimulatory effect of glyphosate on picocyanobacteria communities. Science of the Total Environment, 701, p.134601.

2019- Metz, S., Singer, D., Domaizon, I., Unrein, F. and Lara, E., 2019. Global distribution of Trebouxiophyceae diversity explored by high‐throughput sequencing and phylogenetic approaches. Environmental Microbiology, 21(10), pp.3885-3895.

2019- Metz, S., Lopes dos Santos, A., Berman, M.C., Bigeard, E., Licursi, M., Not, F., Lara, E. and Unrein, F., 2019. Diversity of photosynthetic picoeukaryotes in eutrophic shallow lakes as assessed by combining flow cytometry cell-sorting and high throughput sequencing. FEMS microbiology ecology, 95(5), p.fiz038.

2019- Singer, D., Metz, S., Unrein, F., Shimano, S., Mazei, Y., Mitchell, E.A. and Lara, E., 2019. Contrasted micro-eukaryotic diversity associated with sphagnum mosses in tropical, subtropical and temperate climatic zones. Microbial ecology, 78(3), pp.714-724.

2019- Huber, P., Cornejo-Castillo, F.M., Ferrera, I., Sánchez, P., Logares, R., Metz, S., Balagué, V., Acinas, S.G., Gasol, J.M. and Unrein, F., 2019. Primer design for an accurate view of picocyanobacterial community structure by using high-throughput sequencing. Applied and environmental microbiology, 85(7).

2019- Wanderley, B.M., Araújo, D.S., Quiroga, M.V., Amado, A.M., Neto, A.D., Sarmento, H., Metz, S. and Unrein, F., 2019. flowDiv: a new pipeline for analyzing flow cytometric diversity. BMC bioinformatics, 20(1), pp.1-10.

2018- Nievas, Y.R., Vashisht, A.A., Corvi, M.M., Metz, S., Johnson, P.J., Wohlschlegel, J.A. and de Miguel, N., 2018. Protein palmitoylation plays an important role in Trichomonas vaginalis adherence. Molecular & Cellular Proteomics, 17(11), pp.2229-2241.

2017- Llames, M.E., Huber, P., Metz, S. and Unrein, F., 2017. Interplay between stochastic and deterministic processes in the maintenance of alternative community states in Verrucomicrobia-dominated shallow lakes. FEMS microbiology ecology, 93(7), p.fix077.

2016- Huber, P., Diovisalvi, N., Ferraro, M., Metz, S., Lagomarsino, L., Llames, M.E., Royo‐Llonch, M., Bustingorry, J., Escaray, R., Acinas, S.G. and Gasol, J.M., 2017. Phenotypic plasticity in freshwater picocyanobacteria. Environmental Microbiology, 19(3), pp.1120-1133.

2016- Metz, S., Cabrera, J.M., Rueda, E., Giri, F. and Amavet, P., 2016. FullSSR: microsatellite finder and primer designer. Advances in bioinformatics, 2016.